The Southern Helgeland coast is a journey through a lush nature, with the ocean, sheltered bays and beaches on the seaward side of the road and mountains and peaks on the other. This coast is rich in tradition, legends and stories.

The Vega Islands are on Unesco's World Heritage List. Over the last 1,500 years, generations of fishermen and farmers have sustained a living in this weatherbitten area with the eider duck as a vital source of livelihood. There are good ferry connections to Vega.

The Seven Sisters north of Alstahaug and Torghatten south of Brønnøysund are well known natural attractions along this stretch of road. The Sisters are a range of seven mountains, all more than 1,000 metres above sea level, that the poet priest Peter Dass is supposed to have named. The 160 metre long hole through Torghatten mountain was created by the ice age. The path through the cave and up to the view out towards islands and sea is a rewarding walk.

The islands and skerries of the Helgeland coast have been made accessible to travellers by ferries and express boats. This stretch of coast is known as the thousand island realm and there are perhaps as many opportunities for activities and experiences there.

The future Helgelandskysten Sør National Tourist Route stretches from Holm to Alstadhaug and is 101 kilometres long.